A Master’s thesis in the Department of Medicinal Chemistry at the College of Medicine, Al-Qadisiyah University, entitled “Modern Biomarkers for Early Detection of Bone Tumors,” was presented by researcher Ahmed Obaid Nahedh, under the supervision of Professor Dr. Ajil Abdul-Hussein Al-Zamili and Assistant Professor Dr. Ali Saleh Mahdi.

The thesis aimed to study the role of these biomarkers as early diagnostic tools and to improve detection accuracy compared to healthy individuals. It also aimed to evaluate a group of biomarkers, including TNF-α, IL-6, Collagen Type I, Alkaline Phosphatase (ALP), and LDH enzyme, in addition to some hematological parameters, and to investigate their ability to predict the development of osteosarcoma.

The thesis recommended the possibility of adopting these simple biomarkers for the early diagnosis of bone tumors, especially in resource-limited settings. It emphasized the need for larger studies to strengthen these findings and apply them clinically, as well as to develop rapid and low-cost tests to improve patient outcomes.