A doctoral thesis at the College of Veterinary Medicine at Al-Qadisiyah University discussed the relationship between coccidiosis and the level of cytokines in the intestines of broiler chickens.


The aim of this thesis was to explore the relationship between Eimeria sp. infection in broiler chickens and the inflammatory response, by measuring the levels of both interleukin-2 (IL-2) and interleukin-4 (IL-4). This relationship was assessed from two aspects related to tissue expression: at the gene level (gene expression) and at the protein level.
The most important conclusions: Elevated levels of the cytokine genes IL-2 and IL-4 were detected in infected broiler chickens within the cecal tonsils. Positive expression of IL-2 and IL-4 proteins was also identified in epithelial cells.
The most important recommendations: Measure the levels of cytokine genes in organs other than the cecum, such as the spleen, thymus, and Peyer’s patches. This contributes to a more comprehensive understanding of the immune response in various tissues.

 

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